Methyl B-12 & Methyl Folate Lemon
100 Chewable Tablets / 3 Months Supply
Jarrow Formulas® Methyl B-12 & Methyl Folate plus Pyridoxal-5-Phosphate (P5P) combines the biologically active coenzyme forms of vitamin B12, B9 and B6 that support cellular energy metabolism and neurotransmitter synthesis.* This combination supports the recycling of homocysteine to methionine to support cardiovascular health.*
Summary
Serving Size: 1 Tablet
Amount Per Serving
% Daily Value
Vitamin B6 (as Pyridoxal-5-Phosphate)
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt])
Vitamin B12 (as Methylcobalamin)
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
‡Dietary Folate Equivalents.
Quatrefolic® is a registered trademark of Gnosis S.p.A. Protected by U.S. Patent # 7,947,662.
Store in a cool, dry place.
About Methyl B-12 & Methyl Folate Lemon
How it works
This formula combines the biologically active forms of three B vitamins: methylcobalamin (B12), methylfolate (B9), and pyridoxal-5-phosphate (B6). Active forms matter because a portion of the population carries MTHFR gene variants that impair conversion of synthetic folic acid and cyanocobalamin; the methylated forms arrive ready to use.* Together, these vitamins support cellular energy metabolism, neurotransmitter synthesis, and the recycling of homocysteine to methionine, which supports cardiovascular health.*
Who it's for
People with known or suspected MTHFR variants, those on plant-based diets where B12 is scarce, older adults with reduced absorption, and anyone preferring a pleasant lemon chewable over pills.*
Frequently Asked Questions
It combines the biologically active coenzyme forms of vitamins B12 (methylcobalamin), B9 (methylfolate), and B6 (P5P) to support cellular energy metabolism and neurotransmitter synthesis.* Together they support the recycling of homocysteine to methionine, which supports cardiovascular health.*
Many people carry MTHFR gene variants that reduce conversion of synthetic folic acid and cyanocobalamin into active forms. Methylfolate and methylcobalamin arrive already active: no conversion required.*
Chew one lemon-flavored tablet daily, with or without food. Chewables allow absorption to begin in the mouth and make daily B-vitamin support easy for people who dislike swallowing pills.
Yes, the chewable tablets are vegan, gluten-free, and non-GMO. See the label for the sweetening system and full supplement facts.
People with MTHFR variants, those following plant-based diets (B12 is scarce in plant foods), older adults with reduced B12 absorption, and anyone supporting energy metabolism and heart health.* Ask your healthcare provider about testing and individual needs.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Key Ingredients
- NON-GMO
- VEGAN
- GLUTEN FREE
02 Methyl Folate
03 Methyl B-12
Benefits that get better with time
Your body starts absorbing and utilizing active ingredients. A consistent daily intake allows nutrient levels to build toward effective concentrations.
With steady levels established, the formula starts working with your body's natural processes. This is where quality ingredients and clinically relevant doses begin to show.
Compounding benefits take hold. Sustained, balanced support builds over time, and many customers report this is when they start to feel a noticeable difference.
Research & References
- NIH Office of Dietary Supplements, Folate Fact Sheet for Health Professionals. View study
- NIH Office of Dietary Supplements, Vitamin B12 Fact Sheet for Health Professionals. View study
Why Jarrow Formulas
Science first, since 1977. For nearly five decades, Jarrow Formulas has formulated supplements around published science: the clinically studied ingredient forms, at the doses research actually used.
- Clinically studied ingredients. We use the specific branded forms found in published human research: GR-1 and RC-14 probiotic strains, Cognizin citicoline, StimuCal MCHA calcium, Kaneka ubiquinol, and more.*
- Bioavailable active forms. Your body shouldn't have to convert what it can absorb directly. That's why we use methylated B12 and folate instead of synthetic forms, and ubiquinol instead of standard Co-Q10 along with enhanced-absorption delivery systems.*
- Purity you can verify. Non-GMO ingredients, gluten-free and vegan options across the line, and quality controls like citrinin-avoidance fermentation and freeze-dried protein processing.
- Formulated to matter. Clinically relevant doses, strain-level identification on probiotics, and supplement facts that say exactly what is inside.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.















