SAMe - 200mg
200 mg / 20-60 Enteric-Coated Tablets / 1-2 Months Supply
Jarrow Formulas® SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
With More of the Biologically Active S,S than R,S Form
Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made by microbiological fermentation and then processed without chemical solvents to preserve 68-80% (S,S) SAMe.
SAMe supports:
Brain Metabolism and Mood*
SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes.* It has also been proposed to be involved
in the formation or metabolism of neurotransmitters, which helps to
support a balanced mood.*
Joint Health*
SAMe supports the production of healthy connective tissue through transulfuration.* In this transsulfuration process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage.*
Liver Function*
SAMe supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.*
Jarrow Formulas® SAMe 200 is foil blister-packed to maximize stability and provides 200 mg S-Adenosyl Methionine derived from 400 mg of SAMe Tosylate Disulfate.
Summary
Serving Size: 1 Tablet
Amount Per Serving
% Daily Value
S-Adenosyl Methionine (from 400 mg of SAMe Tosylate Disulfate)
† Daily Value (DV) not established.
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame.
EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.
Key Ingredients
- NON-GMO
- VEGAN
- GLUTEN FREE
Benefits that get better with time
Your body starts absorbing and utilizing active ingredients. A consistent daily intake allows nutrient levels to build toward effective concentrations.
With steady levels established, the formula starts working with your body's natural processes. This is where quality ingredients and clinically relevant doses begin to show.
Compounding benefits take hold. Sustained, balanced support builds over time, and many customers report this is when they start to feel a noticeable difference.
Why Jarrow Formulas
Science first, since 1977. For nearly five decades, Jarrow Formulas has formulated supplements around published science: the clinically studied ingredient forms, at the doses research actually used.
- Clinically studied ingredients. We use the specific branded forms found in published human research: GR-1 and RC-14 probiotic strains, Cognizin citicoline, StimuCal MCHA calcium, Kaneka ubiquinol, and more.*
- Bioavailable active forms. Your body shouldn't have to convert what it can absorb directly. That's why we use methylated B12 and folate instead of synthetic forms, and ubiquinol instead of standard Co-Q10 along with enhanced-absorption delivery systems.*
- Purity you can verify. Non-GMO ingredients, gluten-free and vegan options across the line, and quality controls like citrinin-avoidance fermentation and freeze-dried protein processing.
- Formulated to matter. Clinically relevant doses, strain-level identification on probiotics, and supplement facts that say exactly what is inside.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.















