Study Shows the Effectiveness of Oral Probiotic Lp299v in Treating Symptoms Associated with IBS

Los Angeles, CA, November 24, 2010 The results of a study presented in May at Digestive Disease Week (DDW) by Prof. Philippe Ducrott©, from Rouen University Hospital, in France, demonstrated that the probiotic strain Lactobacillus plantarum 299v (LP299v) has been shown to be effective for the relief of gastrointestinal symptoms, particularly abdominal pain and bloating, in Irritable Bowel Syndrome (IBS) patients fulfilling the Rome III criteria.

Jarrow Formulas Ideal Bowel Support 299v is a branded probiotic product consisting of the exact strain, Lp299v, used in the study. Ideal Bowel Support 299v is an oral probiotic supported by more than 10 years of clinical studies that have shown to alleviate digestive discomfort, bloating, bouts of constipation and occasional diarrhea.

The study enrolled 214 patients (63 women and 151 men) fulfilling the Rome III criteria for IBS. The randomized placebo-controlled trial was conducted over a four-week period and consisted of a daily capsule of placebo or Lp299v equivalent to 10 CFU/day. IBS symptoms were monitored, including the following:
    • Frequency of abdominal pain
    • Intensity of abdominal pain
    • Bloating
    • Number of stools
    • Feeling of incomplete rectal evacuation
The study showed that:
    • After four weeks of treatment, Lp299v significantly improved the symptoms, in particular abdominal pain and bloating, as compared to both baseline and the placebo group.
    • The overall patient's assessment of the treatment was significantly better in the Lp299v group compared to the placebo group.
Jarrow Formulas Ideal Bowel Support 299v® contains Probias proprietary probiotic strain Lactobacillus plantarum 299v (Lp299v) which has been shown in clinical trials to survive and colonize the digestive tract and alleviates intestinal discomfort in 95% of the patients studied. IBS 299v also promotes regularity, enhances intestinal comfort and optimizes immune function. Ideal Bowel Support 299v® contains 10 billion beneficial organisms per vegetarian capsule and does not require refrigeration.  It is also both dairy and gluten free.

In this current study, Lp299v supplication resulted in a 2-3 fold reduction in abdominal pain and bloating scores compared to the placebo, says Kaori Dadgostar, Ph.D, Technical Specialist for Jarrow Formulas. This unique probiotic strain can provide a new probiotic alternative for people who need an additional boost to their gastrointestinal health. Jarrow Formulas Ideal Bowel Support 299v is another in a long line of efficacious Jarrow probiotic offerings, providing answers to condition-specific needs.

Ideal Bowel Support 299v® is manufactured at a Good Manufacturing Practices (GMP) pharmaceutical facility under strict quality control to ensure potency and consistency.

Jarrow Formulas is a nutritional supplement formulator and marketer founded in 1977 and incorporated in 1988. The company markets its products throughout the United States and internationally in more than 20 countries in Europe, Asia, Israel, Azerbaijan and Latin America. The company offers a complete line of nutritional products that includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition formulations. Jarrow Formulas, Inc. is active in regulatory affairs, helping to maintain Americans rights to free access to dietary supplements. Its products are manufactured by Jarrow Industries Incorporated, a GMP-certified, pharmaceutical quality facility located in Santa Fe Springs, CA.