SAMe
S-Adenosyl Methionine
Promotes: Joint Strength* Liver Detoxification* Mood and Brain Function*
SAMe Highlights
  • Enteric-Coated
  • Central biochemical building block
  • Body's primary methyl donor*
  • 68-80% Active S,S Form
  • Made Naturally By Fermentation
  • Individually Blister-Packed
What Does SAMe Do?

Jarrow Formulas® SAMe 200 provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S,S Form

Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule and consists of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAMe is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAMe, the highest active level available.

SAMe has been clinically shown to have the following benefits:

Joint Strength

SAMe supports the production of healthy connective tissue through transulfuration.* In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.*

Brain Metabolism

SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*

Liver

SAM metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase) which are components of the body’s endogenous antioxidant network and important for liver function, including phase II detoxification.*

Jarrow Formulas® SAMe 200 is foil blister-packed to maximize stability and safety. DO NOT use if outer seal of blister pack is broken.

Full Potency 200 mg SAMe (net yield) is derived from 400 mg of SAMe tosylate disulfate.

For best results, use with Jarrow Formulas® JarroSil®, the biologically Activated Silicon®.

Store in a cool, dry place.

Suggested Usage

Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.

WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using this product. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAMe. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.

Other Ingredients

Cellulose, mannitol, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, sodium starch glycolate. Enteric coating consists of modified cellulose, triethyl citrate, magnesium silicate and riboflavin.

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

EnteroGuard® is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resists stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.

Suitable for vegetarians/vegans.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Product Information
20 Enteric-Coated Tablets
200 mg SAMe Per Serving
Code: SAMEBX
Product #: 120014
Reformulation Date: 04/30/2013
Design Change Date: 08/26/2013
Last Update: 07/24/2017

Keep out of the reach of children.